Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution
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منابع مشابه
Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution.
Native mass spectrometry is a rapidly emerging field for characterising the structure of proteins and protein assemblies. The technique relies on electrospray ionisation (ESI) to efficiently ionise the protein analyte and transmit it into the gas phase with retention of protein structure, non-covalent protein-ligand and protein-protein interactions. In native ESI, both the ionisation efficiency...
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ژورنال
عنوان ژورنال: The Analyst
سال: 2015
ISSN: 0003-2654,1364-5528
DOI: 10.1039/c4an02334j